Showing posts with label lipid. Show all posts
Showing posts with label lipid. Show all posts

Monday, April 26, 2010

Male monkeys hold babies to make friends

A cute infant will apparently attract attention no matter what the species

It's easy to make friends when you are holding a baby, suggests a new study that found male Barbary macaques have a better chance of bonding with each other when at least one is hauling around an infant.

The study, which has been accepted for publication in the journal Animal Behavior, is among the first to demonstrate that infants likely serve as social tools for at least some primates. Like a human father pushing around junior in a stroller or walking a gentle dog, the presence of a cute, young, defenseless being seems to alleviate tension when meeting others.
When a Barbary macaque male encounters another male with an infant, a "bizarre ritual" takes place, co-author Julia Fischer told Discovery News.
Fischer said the males "sit together, embrace each other, then they hold up the infant and nuzzle it. Their teeth chatter and lip smack while making low frequency grumbling noises."
This can go on for quite a few minutes.
"Sometimes the males part," she added. "But sometimes they just sit there, holding the infant, and some time later proceed through this ritual once more. These interactions require an infant, so to speak, and the assumption is that carrying an infant is attractive because it allows you to interact with other males in this way."
 

Fischer and colleagues Stefanie Henkel and Michael Heistermann conducted the study at an outdoor enclosure at La Foret des Singes in Rocamadour, France. It's a park where the monkeys can range freely, with human visitors restricted to a path.
The researchers documented encounters between male macaques, and also took chemical samples from the males' feces to measure their physiological stress. The scientists found that males toting infants — not even always their own — had stronger ties with other males than non-carriers. Male relationships, as a result, tended to be stronger during the spring than during the autumn.
Males who worked their networks in such a way tended to rise up the monkey social ladder. For example, one male rose from fifth to second place after acquiring "the highest number of male partners."
Using infants as a "social tool," however, came with a cost. The researchers found the baby-hauling males were more stressed out because the often-crying infants got on the carriers' nerves.
Macaque infant crying "very much sounds like (human) baby crying," Fischer said. "The acoustic structure is very similar, just a little bit more high pitched, but very noisy and variable, so nobody can get used to it."
"It does not surprise me that using infants (as social tools) causes stress in males," Anthropologist Meredith Small at Cornell University told Discovery News. "I've seen it and it's intense."

 

Tuesday, January 19, 2010

Nano technology tackles heart disease

A molecule designed to find, latch onto, then treat hardened arteries could offer a new way to tackle heart disease, say its inventors.

Nanoburrs, developed at the Massachusetts Institute of Technology (MIT), target only damaged cells in blood vessel walls.                                                                   
Once attached, they can release drugs in precisely the right place.
But the British Heart Foundation warned the technology was some years from being used in patients.
The hardening of the arteries which supply the heart, or atherosclerosis, can eventually lead to blockages which can cause heart attacks.
The study in the Proceedings of the National Academy of Sciences journal says specialists normally use tiny balloons to force open the vessels, then place a tube called a stent inside to keep it open.
Often the process triggers a rapid re-growth of tissue around the stent which can lead to the artery blocking again, and a recent advance has been a stent which releases drugs for a number of days after insertion to keep this process under control.
The MIT approach offers another way to get these drugs to exactly the right place.
Its nanoburrs are coated with proteins which can only stick to a structure in the blood vessel wall called the "basement membrane".
This is only exposed when the wall is damaged, so only damaged sections of blood vessel are targeted.
Once in place, a reaction takes place to release the drug over a prolonged period - up to 12 days so far.
Long way off
Professor Robert Langer, one of the authors of the research, said: "This is a very exciting example of nanotechnology and cell targeting in action."
He said the technology could target any condition in which the cell wall was compromised in this way, including certain types of cancer, and other inflammatory diseases.
Professor Peter Weissberg, medical director of the British Heart Foundation, said that while the technology was "promising", there were many time-consuming obstacles to overcome before it could be regularly used in patients.
He said: "This is an interesting proof of principle. People have been looking for a long time for ways to target a particular drug to a particular part of the body.
"It wouldn't be able to replace the need for a balloon and stent to open an artery, but it's possible that one day, it may be able to deliver a drug to treat atherosclerosis itself."
Nanoburr diagram